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KMID : 1151820200140060747
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Journal of the Korean Society of Radiology
2020 Volume.14 No. 6 p.747 ~ p.753
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Radiation Protection Effect of Mixed Extracts of Artemisia asiatica Nakai and Moringa oleifera Lam on Rats Uterus
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Lee Yoon-Ji
Kim Jang-Oh
Jeon Chan-Hee
Lee Ji-Eun
Jeong Geun-Woo
Jung Do-Young
Min Byung-In
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Abstract
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The purpose of this study was to examine the potential for the development of radioprotective agent in extracts manufactured by mixing Artemisia asiatica Nakai and Moringa oleifera Lam known as antioxidant food with the appropriate ratio. Their whole body were irradiated 7Gy radiation after oral administration of a mixed extract of Artemisia asiatica Nakai and Moringa oleifera Lam to SD Rat for two weeks. And 1 day, 7days, 21days later, changes in blood cell components, SOD activations and tissue changes in the uterus were observed.It was confirmed that the AM + IR group had a higher tendency to recover leukocyte (p<0.05) and platelet (p<0.05) levels than the IR group. It was also confirmed that SOD activity was increased and cell death was decreased in uterine tissue.Based on these results, the mixed extract of A and B is expected to be useful as a radiation protection agent capable of reducing blood cell and uterine damage caused by radiation exposure.
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KEYWORD
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Artemisia asiatica Nakai, Moringa oleifera Lam, Antioxidant, Radioprotective agent
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